Abstract: Strabismus and amblyopia are common and closely related eye diseases. The damage to the corrected visual acuity, stereo vision and other related visual functions and changes in appearance will affect the quality of life(QoL) of patients. QoL is an important indicator for comprehensive evaluation of patients' physical and mental health. At present, there are special scales in the field of strabismus and amblyopia for the evaluation and selection of different subjects. The apparent decline in the QoL of strabismus patients is mainly affected by binocular vision function, the appearance of strabismus and social evaluation, and it will be significantly improved after surgery and other treatments. The QoL of amblyopia patients is relatively normal, but it is susceptible to early patching treatment and declines, and as the treatment effect improves, it gradually improved.